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Melanotan II (10mg)

Melanotan II (10mg)

Regular price $59.99
Regular price $59.99 Sale price
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Research Use Only

This product is sold for research purposes only. It is not intended for human or animal consumption. By purchasing this product, you confirm that you are a qualified researcher or are purchasing for legitimate research purposes.

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Melanotan II (10mg)

Melanotan II (10mg)

Regular price $59.99
Regular price $59.99 Sale price
SAVE Sold out

Shipping Information

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Melanotan II

Supplied as a lyophilized (freeze-dried) white powder in a sealed sterile vial. Requires reconstitution with bacteriostatic water prior to use. Each vial contains 10mg of Melanotan II at ≥99% purity.

Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), acting as a non-selective melanocortin receptor agonist across multiple melanocortin receptor subtypes. Its cyclic structure — stabilised through a lactam bridge between the Asp and Lys residues — confers considerably greater potency and metabolic stability than native α-MSH. It has been extensively researched for its role in melanogenesis and pigmentation, and is studied for two of the most-examined outcomes in melanocortin research: melanin synthesis and libido modulation, alongside broader research into appetite regulation and central nervous system melanocortin activity.

Research Background

Research has examined Melanotan II's activity across the melanocortin receptor family, particularly MC1R (linked to melanogenesis and pigmentation) and MC3R/MC4R (linked to appetite regulation, energy homeostasis, and central nervous system effects on sexual function). Its non-selective receptor profile makes it a useful comparative tool for distinguishing which physiological effects are mediated by which melanocortin receptor subtype, relative to more selective analogues. Studies have also investigated its photoprotective potential, given its ability to stimulate melanin synthesis with reduced dependence on UV exposure compared to natural tanning pathways.

Key Research Areas
Melanogenesis & pigmentation — stimulates melanin synthesis with reduced UV dependency
Libido & sexual function — studied for effects on arousal and erectile response
Appetite modulation — studied for appetite reduction and caloric regulation
Mood & motivation — associated with central melanocortin system activity
Studied Mechanisms
Non-selective agonism across MC1R, MC3R, and MC4R melanocortin receptors
Tyrosinase pathway upregulation driving eumelanin synthesis (MC1R)
Central MC4R activation linked to appetite suppression and sexual response
Cyclic lactam-bridge structure conferring enhanced receptor binding stability

Product Specifications

Molecular FormulaC₅₀H₆₉N₁₅O₉
Molecular Weight1,024.2 g/mol
CAS Number121062-08-6
SequenceAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
AppearanceLyophilised Powder
Purity≥99% (HPLC Verified)
StorageStore at -20°C, away from light and moisture
Research Use Only

This product is strictly intended for in vitro laboratory research purposes only. It is not approved for human or veterinary use, and is not intended for consumption, injection, or any therapeutic application.