PT-141 (10mg)

PT-141 (10mg)

$69.99
$69.99
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Research Use Only

This product is sold for research purposes only. It is not intended for human or animal consumption. By purchasing this product, you confirm that you are a qualified researcher or are purchasing for legitimate research purposes.

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PT-141 (10mg)

PT-141 (10mg)

$69.99
$69.99
SAVE Sold out

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PT-141

Supplied as a lyophilized (freeze-dried) white powder in a sealed sterile vial. Requires reconstitution with bacteriostatic water prior to use. Each vial contains 10mg of PT-141 at ≥99% purity.

PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), acting as a central melanocortin receptor agonist. It is studied for CNS-mediated mechanisms — acting on melanocortin receptors (MC3R and MC4R) in the brain rather than through peripheral vascular pathways. This distinguishes PT-141 from PDE5 inhibitors (sildenafil, tadalafil), which act on peripheral vasodilation rather than central nervous system signalling. A modified pharmaceutical form of bremelanotide received FDA approval in 2019 for hypoactive sexual desire disorder in premenopausal women, underscoring the clinical relevance of the research literature surrounding this mechanism.

Research Background

Research on PT-141 has focused on its central neuroendocrine mechanism of action, distinguishing it from peripherally-acting vasodilator compounds. Studies have examined melanocortin receptor (MC3R and MC4R) signalling and its downstream relationship to sexual arousal pathways in both male and female research models — a point of interest given that most established sexual-function research tools act through vascular rather than neurological mechanisms. Because PT-141's activity is not confined to erectile response, it has also been used as a research tool for studying the broader melanocortin system, including its involvement in mood, stress, and reward-related pathways.

Key Research Areas
Sexual arousal pathways — studied for central melanocortin receptor activation in both male and female research models
Hypoactive sexual desire — studied in models where the underlying mechanism is neurological rather than vascular
Cross-sex research — studied across male and female models, distinguishing it from PDE5 inhibitors primarily indicated for male erectile dysfunction
Melanocortin system — research tool for studying melanocortin pathways in mood, motivation, and reward beyond sexual function
Studied Mechanisms
Central MC3R and MC4R receptor agonism in the hypothalamus
Neuroendocrine (rather than vascular) mediation of arousal response
Cyclic lactam-bridge structure conferring receptor binding stability
Melanocortin pathway involvement in mood, stress, and reward signalling

Product Specifications

Molecular FormulaC₅₀H₆₈N₁₄O₁₀
Molecular Weight1,025.2 g/mol
CAS Number189691-06-3
SequenceAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
AppearanceLyophilised Powder
Purity≥99% (HPLC Verified)
StorageStore at -20°C, away from light and moisture
Research Use Only

This product is strictly intended for in vitro laboratory research purposes only. It is not approved for human or veterinary use, and is not intended for consumption, injection, or any therapeutic application.